Aspirin (Acetylsalicyclic acid)

Brand Name: Bayer Aspirin, Ecotrin, Alpyrin, Asalite, Aspicot, Aspin, Ecosprin, Zosprin, Delisprin, Arthritis pain
Generic Name: Aspirin or Acetylsalicyclic acid

About Aspirin (Acetylsalicyclic acid)

What is Aspirin?

Aspirin is one of the salicylate drug, which helps to cure fever, pain, inflammation and has anti-coagulation effect (stops blood cells from sticking to each other and forming a clot). It is also called as Acetylsalicyclic acid.

Aspirin belongs to a group of drugs called NSAID (Non steroid Anti-Inflammatory Drug). Other drugs of same group are naproxen, paracetamol, ibuprofen, indomethacin and so many others.

Aspirin was first discovered in 1897 by Felix Hoffman of Friedr Bayer & Co. who was finding a cure for his father’s arthritic pain. Aspirin was the worlds first stable pain reliever in tablet form and was registered in 1899 in Imperial Patent Office in Berlin.

How is Aspirin (Acetylsalicyclic acid) used?

Aspirin can be found in market in tablets (coated, chewed and dispersible forms). An injectable preparation has also been made available. It is strongly recommended not to chew or crush Aspirin coated tablet as it should be ingested whole.

Aspirin should be used only after taking food.

Aspirin is an OTC (Over The Counter) drug meaning Aspirin can be bought without doctor’s prescription but you are advised to consult your doctor before taking Aspirin, especially if you are going to use Aspirin for any other diseases.

How does Aspirin (Acetylsalicyclic acid) work?

Aspirin suppresses the production of different chemicals in our body. Aspirin affects the production of:

  • Prostaglandin -This hormone is responsible for providing pain information to brain
  • Thromboxaneit causes sticking of platelets to each other, which may lead to clots formation and produce risks of many diseases

It permanently inactivates Cycloxygenase 1(COX-1) that helps in production of prostaglandin and modifies the structure of Cycloxygenase 2 (COX-2) respectively.

Since other NSAIDs inhibits COX-1 and 2 receptors reversibly or temporarily. But aspirin inhibits the COX-1 and COX-2 receptors permanently. This might be the major reason why aspirin is more effective than other drugs of the same category, NSAIDs (Non-Steroidal Anti-Inflammatory Drugs)